ABSTRACT
Objective: To study the chemical constituents from the aerial parts of Chloranthus angustifolius. Methods: The chemical constituents were isolated by various chromatography techniques and their structures were elucidated on the basis of physiochemical properties and spectrascopic analysis. Results: Eight compounds were isolated and identified as 1-acetoxy-2,3,4,5- tetrahydroxy-5-p-metoxyphenylpentane (1), (E)-5-(4-methoxyphenyl) pent-4-ene-1,2,3-trihydroxyamyl (2), isofraxidin (3), (-)-dihydrodehydrodiconiferyl alcohol (4), (±)-erythro-guaiacyl-glycerol-β-O-4'-dihydroconiferyl ether (5), (-)-rosiridol (6), (4S)-p-menth-1-ene-4,7-diol (7), and loliolide (8), respectively. Conclusion: Compounds 1 and 2, named chloranthus pentitol and chloranthus enol, are two new p-methoxyphenyl pentitol derivatives, while compounds 3-8 are obtained from C. angustifolius for the first time.
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the monolayer wide-edge continuous suture anastomosis in order to explore the method to prevent or reduce the frequency of anastomotic fistula and stenosis.</p><p><b>METHODS</b>936 esophageal cancer patients were divided into two groups: 468 by monolayer wide-edge continuous suture anastomosis with absorbable suture at esophagogastrostomy; while the other 468 by regular interrupted suture anastomosis with silk thread as control. The complication such as anastomotic fistula and stenosis in two groups were compared.</p><p><b>RESULTS</b>In the group treated by monolayer wide-edge continuous suture anastomosis, there were 1 fistula (0.2%) and 1 stenosis (0.2%) versus 8 fistula (1.9%) and 11 stenosis (2.4%) in the control group. There was a statistically significant difference between two guoups was observed (P < 0.05).</p><p><b>CONCLUSION</b>Monolayer wide-edge continuous suture anastomosis at esophagogastrostomy for esophageal cancer patient may effectively prevent or reduce the frequency of anastomotic fistula and stenosis.</p>